PROCEPT Spray Dryer / Chiller GMP
Spray Drying is the most advanced instant drying process to engineer a particle and formulate in a single step. The SDx series of Spray Dryers feature closed loop solvent processing under nitrogen. The unit is capable of spray drying/chilling/congealing samples of a few ml to batches of several liters.
The PROCEPT Spray Dryer / Chiller GMP allows straight transfer from the PROCEPT R&D Spray Dryer without scale-up! The unit is built through the GMP wall or wheelable stand-alone in the GMP room.
PROCEPT’s parallel Spray Dryer / Chiller GMP set-up avoids scale-up from R&D to Clinical production. This flexible parallel concept provides the fastest route to the market of your small molecules and biologics.
The PROCEPT Closed Loop Spray Dryer / Chiller GMP
Increase your spray drying capacity without scale-up problems using multiple columns with a single central control system. Our modular system has several very important advantages including:
- Faster time to market.
- Fewer production risks.
- Flexible production capacity.
- Phased investment capacity follows your needs.
- Fits into standard infrastructure.
- First small clinical batches without scale-up issues.
Features
High process yields (>90%) from a few ml to batches of several liters. Particles from 1-350µm Water and organic solvents Different nozzle types: 2-fluid, 3-fluid, cooled, heated, ultrasonic. Chilling or congealing; waxes, polymers, carbohydrates,.. Provision for product cooling for very temperature sensitive or low glass transition temperature products. Touch screen PC control with real-time trending and excel data reporting. Critical process data such as temperatures, pressures, and liquid/gas flows are handled by the control unit. Closed loop solvent processing under N2. Designed for use in Atex Zone 2 areas. Software 21 CFR Part 11 compliant, OPC-UA and LDAP. Possiblity to generate larger particles with better flow characteristics. Stand alone wheelable unit with small footprint. Through the cleanroom wall integration in technical zone. All glass columns, transport tubes, cyclone and product collection vessels for unsurpassed visibility, or Insulated stainless steel columns, stainless transport tubes, cyclone and product receivers, or Combination of glass and stainless steel components.